Beyond Nutrition: Bioactive Profiles and Pharmacological Potential of Major Agricultural Commodities and By-products of Banyumas, Indonesia - A Narrative Review
Keywords:
Banyumas commodities, bioactive profiles, therapeutic potential, raw materials, circular economyAbstract
Background: Banyumas Regency have a high diversity of agricultural commodities; however, their utilization remains largely confined to basic food and economic purposes. Additionally, numerous agricultural by-products and waste materials have not been maximally utilized. Purpose: This review aims to explore the bioactive profiles and therapeutic potentials of major Banyumas commodities to support public health, reduce dependence on imported pharmaceutical raw materials, and promote a circular economy. Methods: A narrative literature review was conducted using various reference sources and reputable journals, with an emphasis on current research. Results: Key commodities such as cashew, coffee, rubber, clove, tobacco, sugarcane, coconut husk, and rice husk demonstrate diverse pharmacological activities, including antioxidant, antimicrobial, anti-inflammatory, antidiabetic, wound healing, and metabolic disorder-modulating effects. Conclusion: Beyond fulfilling nutritional requirements, these primary commodities and their associated waste products hold strong potential as alternative phytopharmaceutical materials, capable of advancing both the circular economy and public health
References
Abdul Aziz, A. H., Rizkiyah, D. N., Qomariyah, L., Irianto, I., Che Yunus, M. A., & Putra, N. R. (2023). Unlocking the Full Potential of Clove (Syzygium aromaticum) Spice: An Overview of Extraction Techniques, Bioactivity, and Future Opportunities in the Food and Beverage Industry. Processes, 11(8), 2453. https://doi.org/10.3390/pr11082453
Akinpelu, D. A., & Obuotor, E. M. (2000). Antibacterial activity of Nicotiana tabacum leaves. Fitoterapia, 71(2), 199–200. https://doi.org/10.1016/S0367-326X(99)00148-3
Al-Lahham, S., Sbieh, R., Jaradat, N., Almasri, M., Mosa, A., Hamayel, A., & Hammad, F. (2020). Antioxidant, antimicrobial and cytotoxic properties of four different extracts derived from the roots of Nicotiana tabacum L. European Journal of Integrative Medicine, 33, 101039. https://doi.org/10.1016/j.eujim.2019.101039
Amalia, F. F. (2020). Aktivitas Antibakteri Kopi Robusta Dalam Mempercepat Kejadian Penyembuhan Luka Pada Ulkus Diabetikum. Healthy Tadulako Journal (Jurnal Kesehatan Tadulako), 6(1), 1–6. https://doi.org/10.22487/htj.v6i1.95
Ameya, G., Manilal, A., & Merdekios, B. (2017). In vitro Antibacterial Activity and Phytochemical Analysis of Nicotiana tabacum L. Extracted in Different Organic Solvents. The Open Microbiology Journal, 11, 352–359. https://doi.org/10.2174/1874285801711010352
Antunes, F., Mota, I. F., Fangueiro, J. F., Lopes, G., Pintado, M., & Costa, P. S. (2023). From sugarcane to skin: Lignin as a multifunctional ingredient for cosmetic application. International Journal of Biological Macromolecules, 234, 123592. https://doi.org/10.1016/j.ijbiomac.2023.123592
Araújo, T. S. L., Costa, D. S., Sousa, N. A., Souza, L. K. M., de Araújo, S., Oliveira, A. P., Sousa, F. B. M., Silva, D. A., Barbosa, A. L. R., Leite, J. R. S. A., & Medeiros, J. V. R. (2015). Antidiarrheal activity of cashew GUM, a complex heteropolysaccharide extracted from exudate of Anacardium occidentale L. in rodents. Journal of Ethnopharmacology, 174, 299–307. https://doi.org/10.1016/j.jep.2015.08.020
Arif, H. S., Arifah Sri Wahyuni, M. S., & Dr. Haryoto, M. S. (2013). Potensi Biolarvasida Ekstrak Etanol Kulit Batang Karet India (Ficus elastica Nois Ex Blume) Dan Uji Toksisitasnya Dengan Metode Brine Shrimps Lethality Test [S1, Universitas Muhammadiyah Surakarta]. https://eprints.ums.ac.id/24187/
Badan Pusat Statistik Kabupaten Banyumas,. (2025). Statistik Daerah Kabupaten Banyumas 2025 . (Vol. 15). (Original work published Badan Pusat Statistik Kabupaten Banyumas)
Badan Pusat Statistik Kabupaten Banyumas. (2026). Kabupaten Banyumas Dalam Angka 2026. Vol. 51. Purwokerto: BPS Kabupaten Banyumas, 2026. ISSN 0215-4331. No. Publikasi 33020.26003.
Banyumas, B. P. S. K. (2025). Produksi Perkebunan Rakyat Menurut Jenis Tanaman di Kabupaten Banyumas (ribu ton), 2025—Tabel Statistik. https://banyumaskab.bps.go.id/id/statistics-table/3/Y0hOWWFGZHpPVkpUVjFKUlowVjBhMUI1Wm1aWFp6MDkjMw==/produksi-perkebunan-rakyat-menurut-jenis-tanaman-di-kabupaten-banyumas--ribu-ton---2022.html
BPOM. (2022). Siaran Pers | Badan Pengawas Obat dan Makanan. https://www.pom.go.id
Buamard, N., & Benjakul, S. (2017). Ethanolic coconut husk extract: In vitro antioxidative activity and effect on oxidative stability of shrimp oil emulsion. European Journal of Lipid Science and Technology, 119(11), 1700131. https://doi.org/10.1002/ejlt.201700131
Burlacchini, G., Sandri, A., Papetti, A., Frosi, I., Boschi, F., Lleo, M. M., & Signoretto, C. (2024). Evaluation of Antibacterial and Antibiofilm Activity of Rice Husk Extract against Staphylococcus aureus. Pathogens, 13(1), 80. https://doi.org/10.3390/pathogens13010080
Cortés-Rojas, D. F., de Souza, C. R. F., & Oliveira, W. P. (2014). Clove (Syzygium aromaticum): A precious spice. Asian Pacific Journal of Tropical Biomedicine, 4(2), 90–96. https://doi.org/10.1016/S2221-1691(14)60215-X
Cyriac, M. B. (2013). Antimicrobial properties of coconut husk aqueous...: Archives of Medicine and Health Sciences. Ovid. https://doi.org/DOI:%2010.4103/2321-4848.123024
de Carvalho Melo-Cavalcante, A. A., de Moura Dantas, S. M. M., de Sousa Leite, A., Matos, L. A., de Castro e Sousa, J. M., Picada, J. N., & da Silva, J. (2011). In vivo Antigenotoxic and Anticlastogenic Effects of Fresh and Processed Cashew (Anacardium occidentale) Apple Juices. Journal of Medicinal Food, 14(7–8), 792–798. https://doi.org/10.1089/jmf.2010.0153
de Lima, A. C. S., Soares, D. J., da Silva, L. M. R., de Figueiredo, R. W., de Sousa, P. H. M., & de Abreu Menezes, E. (2014). In vitro bioaccessibility of copper, iron, zinc and antioxidant compounds of
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